Download PDF
Journal of Pediatric Biochemistry 2013; 03(01): 013-021
DOI: 10.1055/s-0036-1586426
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Gestational diabetes: Potential of prebiotics intervention

Li Shen
a   Department of Clinical Nutrition, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China
,
Michael J. Keenan
b   Louisiana State University Agricultural Center, Baton Rouge, LA, USA
,
Jun Zhou
c   Research Service, Veterans Affairs Medical Center, Washington DC, USA
,
Roy J. Martin
d   Western Human Nutrition Research Center, Davis, CA, USA
› Author Affiliations
Subject Editor:
Further Information

Publication History

05 February 2013

05 February 2013

Publication Date:
01 August 2016 (online)

  PDF Download  Permissions and Reprints

Abstract

Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance with first recognition during pregnancy. With the new IADPSG diagnostic criteria the prevalence of GDM increases significantly worldwide. The potential risks of GDM for mother and child both in the short and long term urge more treatments to be explored. Resistant starches as a prebiotics has been shown possessing multiple health benefits including improving glucose tolerance and insulin sensitivity. Altered gut fermentation and microbiota and sequential enhancement in blood gut peptides (i.e. GLP-1) are suggested mechanisms involved. The goal of this paper is to provide a brief overview on GDM and the role of RS in the treatment of GDM.

Keywords

Resistant starch - gestational diabetes - glycemic control - prebiotics