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Journal of Pediatric Neurology 2016; 14(02): 075-077
DOI: 10.1055/s-0036-1584277
DOI: 10.1055/s-0036-1584277
Case Report
Miller Fisher Syndrome Associated with Parvovirus B19 Infection in a Child
Weitere Informationen
Publikationsverlauf
18. September 2015
09. Februar 2016
Publikationsdatum:
30. Mai 2016 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00029030/201602/lookinside/thumbnails/10-1055-s-0036-1584277_1500011-1.jpg)
Abstract
Miller Fisher syndrome (MFS) is a variant of Guillain–Barré syndrome, and it is typically characterized by the triad of ophthalmoplegia, ataxia, and areflexia. We report a 13-year-old boy affected with MFS associated with parvovirus B19 infection in which immunoglobulin (Ig)G and IgM anti-GQ1b antibodies were not detected. Treatment with intravenous Igs resulted in a progressive and rapid resolution of the clinical features. To our knowledge, this is the first example in the literature of seronegative anti-GQ1b antibody MFS associated with parvovirus B19 infection in childhood. The possible role of other gangliosides is discussed.
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