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DOI: 10.1055/s-0036-1579554
Radiofrequency Denervation for Facet Syndrome: A Meta-Analysis of Treatment Outcomes
Denervação de síndrome facetária por radiofrequência: metanálise de resultados de tratamentosPublication History
10 September 2015
21 December 2015
Publication Date:
02 March 2016 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00028832/201602/lookinside/thumbnails/10-1055-s-0036-1579554_1500022-1.jpg)
Abstract
Objective The aim of this study was to carry out a systematic literature review on the facet syndrome and a meta-analysis of the outcomes of radiofrequency denervation in patients presenting with the syndrome.
Methods A systematic literature review was performed based on 52 articles published from 1999 to 2013, available at Bireme, Scielo, PubMed, and MEDLINE databases. The meta-analysis comprises eight case-control studies, found during the literature review, totaling 440 patients. The heterogeneity of the collected data was assessed using the chi-square test (χ2). To estimate the effect of the proposed correlation, we combined the values of each study with the Mantel-Haensze test, which has fixed effects, using the BioEstat 5.0 software.
Results The selected studies were statistically relevant when grouped, determining an effect in favor of the use of facet denervation as a technique capable of relieving chronic low back pain in pre-determined periods of follow-up (OR = 1.251; 95% CI: 1.028–1.524).
Conclusion The results of the systematic literature review and meta-analysis herein presented may be used for the creation of diagnosis and management protocols for facet syndrome, and can also attract the interest of other researchers to conduct further studies on the theme.
Resumo
Objetivo Este estudo teve como objetivo elaborar uma revisão sistematizada sobre síndrome facetária e uma metanálise sobre os desfechos do tratamento neurocirúrgico com denervação por radiofrequência em pacientes acometidos por esta síndrome.
Métodos A revisão sistematizada foi elaborada com base em 52 artigos publicados de 2000 a 2013, disponíveis nas bases de dados eletrônicos Bireme, Scielo, PubMed e MEDLINE. A metanálise foi composta por oito casos-controle, selecionados durante a revisão, totalizando 440 pacientes. Os dados coletados foram avaliados quanto à sua heterogeneidade pelo teste qui-quadrado (χ2). Para estimar o efeito da correlação proposta, os valores de cada estudo foram combinados com o teste de Mantel-Haensze, que tem efeitos fixos, utilizando o software BioEstat 5.0.
Resultados Os estudos selecionados são estatisticamente relevantes quando agrupados, determinando um efeito a favor do uso da denervação facetária como técnica capaz de diminuir a lombalgia crônica em seguimentos pré-determinados, mostrando OR de 1,251 e IC95% entre 1,028 e 1,524.
Conclusão Os resultados da revisão sistemática de literatura e da metanálise aqui apresentados podem servir de base para a criação de protocolos de diagnóstico e conduta da síndrome facetária, assim como despertar o interesse de outros pesquisadores para a condução de novos estudos sobre o tema.
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