Planta Med 2016; 82 - PC89
DOI: 10.1055/s-0036-1578791

Characterization And Assessment Of Ingredients In Sports Dietary Supplements By NMR Approach

J Zhao 1, M Wang 1, B Avula 1, IA Khan 1, 2, 3
  • 1National Center for Natural Products Research
  • 2Department of Pharmacognosy, School of Pharmacy, University of Mississippi, University, MS 38677, USA
  • 3Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

Sports dietary supplements contain variable amounts of ingredients or even ingredients not listed on the label. High-profile adulteration and contamination of banned substances, such as anorectic or androgenic compounds, have made such products the category of the most safety-concerned dietary supplements [1, 2]. To address the issue, a nuclear magnetic resonance (NMR) method was developed to detect adulteration in sports dietary supplements collected from the market. The labeled and unlabeled ingredients in the products, including creatine, β-alanine, taurine, caffeine, arginine, 1, 3-dimethylbutylamine (DMBA), carnitine and malic acid, were characterized and quantified. The method can be used in detecting adulterants and in controlling dietary supplements.

Fig. 1

Acknowledgements: This work was supported in part by “Science Based Authentication of Dietary Supplements” funded by the Food and Drug Administration grant numbers 1U01FD004246 – 05, and the United States Department of Agriculture, Agricultural Research Service, Specific Cooperative Agreement No. 58 – 6408 – 1-603 – 07.

References: [1] Petroczi, A; Taylor, G; Naughton, D.P. (2011) Food Chem. Toxicol., 49, 393. [2] Marijana, Z. K.; Tomczyk, M. (2013) Current drug targets 14(9): 1079 – 1092.