Planta Med 2016; 82 - PC56
DOI: 10.1055/s-0036-1578758

Chemical Constituents From Fadogia Agrestis

A Galal Osman 1, Z Ali 1, BM Oluwasesan 1, 2, RST Kamdem 3, IA Khan 1, 4
  • 1National Center For Natural Products Research
  • 4Division of Pharmacognosy, Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University, MS, 38677, USA
  • 2Department of Applied Chemistry, Federal University Dutsin-Ma, Katsina State, Nigeria
  • 3Department of Organic Chemistry, Higher Teachers Training College, University of Yaounde I P.O. Box 47, Yaounde, Cameroon

Fadogia agrestis Schweinf ex Hiern (Rubiaceae) is an African shrub. In African traditional medicine, it is reputed for its fever reducing utility, kidney pain alleviation, and diuretic effect [1]. The aqueous extract of this plant exhibited potential aphrodisiac properties [2]. Four ursane-type triterpenoid glycosides, two benzophenone glycosides, and one iridoid glucoside, including three new compounds have been isolated and characterized from the dried roots of F. agrestis. The identity of all compounds has been accomplished, primarily, based on 1D and 2D NMR and HRESMS analysis.

Fig. 1

Acknowledgements: This research is supported in part by “Science Based Authentication of Dietary Supplements” funded by the Food and Drug Administration grant number 1U01FD004246 – 05.

References: [1] Anero R, et al. (2008) Phytochemistry, 69: 805 – 811. [2] Yakubu MT, et al. (2005) Asian Journal of Andrology, 7: 399 – 404.