Planta Med 2016; 82 - PC45
DOI: 10.1055/s-0036-1578747

Chemical Constituents Of Tribulus Terrestris L.

FX Wang 1, 2, XG Sun 1, ZF Wang 1, LP Kang 1, KL Wu 1, Y Zhao 1, BP Ma 1
  • 1Beijing Institute of Radiation Medicine, Beijing 100850, PR China
  • 2Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China

Tribulus terrestris L. is a well-known herb distributed in the warm regions all over the world. As a traditional Chinese medicine, it was used in treating cardiovascular diseases, abdominal distention, and high blood pressure, while in Europe it was used as folk medicine against sexual impotence [1]. The difference of biological activity should depend on the difference of chemical composition of T. terrestris collected from different geographical origins. For the purposes of analysis of chemical differences of different regions, UPLC-Q/TOF MSE coupled with multivariate statistical analysis was performed. The results presented by PCA and OPLS-DA revealed that the compounds existed in the samples from China were different from Europe's ones, such as Italy. In order to evaluate the biological activities of T. terrestris further, phytochemical study was carried out. Finally, nineteen new steroidal glycosides, including twelve furostanol saponins and seven spirostanol saponin, together with seventeen known steroidal saponins were isolated [2]. The steroidal saponins exhibited strong effects on cardiovascular activity.

References: [1] Dragomir D, Bogdan J, et al. (2008) Phytochemistry, 69: 176 – 186. [2] LP Kang, KL Wu, HS Yu, et al. (2014) Phytochemistry, 107: 182 – 189.