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DOI: 10.1055/s-0036-1578730
Flavonoid C- And O-Glycosides From Aspalathus Linearis
Aspalathus linearis (N. L. BURM.) R. DAHLGR. is a leguminous shrub endemic to the western parts of the Cape region in South Africa. The leaves and stems are used for the production of rooibos tea which is a quaffable drink because it contains no caffeine and low levels of tannin and lately has attracted attention as a health drink [1]. Beside antioxidant properties, it also shows estrogenic activity and promising consequences as antiallergy, antispasmodic, and hypoglycemic activity [1, 2]. Phytochemical investigation of A. linearis (Rooibos tea) leaves resulted in the isolation and characterization of eleven flavonoid C- and O-glycosides. Structure elucidation was achieved by 1D, 2D NMR experiments and HRESIMS.
Acknowledgements: This research is supported by “Science Based Authentication of Dietary Supplements” funded by the Food and Drug Administration grant number 1U01FD004246 – 05.
References: [1] Shimamura, N., Miyase, T., et al. (2006). Phytoestrogens from A. linearis. Biological & Pharmaceutical Bulletin Biol. Pharm. Bull., 1271 – 1274. [2] Kawano, A., Nakamura, H., et al. (2009). Hypoglycemic effect of aspalathin, a rooibos tea component from A. linearis, in type 2 diabetic model db/db mice. Phytomedicine, 437 – 443.