Journal of Pediatric Biochemistry 2015; 05(03): 098-102
DOI: 10.1055/s-0036-1571832
Original Article
Georg Thieme Verlag KG Stuttgart · New York

The Relationship of Gastrin Levels with Obesity Anthropometrics, Lipid, Glucose, and Insulin Levels in Children and Adolescents with Obesity

Sultan Kaba
1   Division of Pediatric Endocrinology, Department of Pediatrics, Yüzüncü Yil University, Van, Turkey
,
Murat Doğan
1   Division of Pediatric Endocrinology, Department of Pediatrics, Yüzüncü Yil University, Van, Turkey
,
Keziban Aslı Bala
1   Division of Pediatric Endocrinology, Department of Pediatrics, Yüzüncü Yil University, Van, Turkey
,
Kamuran Karaman
1   Division of Pediatric Endocrinology, Department of Pediatrics, Yüzüncü Yil University, Van, Turkey
,
Selami Kocaman
1   Division of Pediatric Endocrinology, Department of Pediatrics, Yüzüncü Yil University, Van, Turkey
› Author Affiliations
Further Information

Publication History

16 September 2015

06 November 2015

Publication Date:
09 February 2016 (online)

Abstract

The aim of the study was to compare the gastrin levels in obese and healthy children and to investigate the relationship of gastrin with obesity anthropometrics, lipid, and baseline insulin levels, and oral glucose tolerance test scores. Gastrin was significantly lower in the obese group compared with the control group (p > 0.001). Gastrin level displayed a negative correlation with body weight, body weight standard deviation, and insulin levels in oral glucose tolerance test at 120 minutes, a positive correlation with glycohemoglobin A1c.The results revealed that there is a significant difference between the gastrin levels in obese and healthy children.

 
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