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J Neurol Surg Rep 2015; 76(02): e233-e238
DOI: 10.1055/s-0035-1562852
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Sinonasal Phosphaturic Mesenchymal Tumor: A Rare and Misinterpreted Entity

Demetri Arnaoutakis
1   Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, United States
,
Iman Naseri
2   Department of Otolaryngology-Head and Neck Surgery, University of Florida College of Medicine, Jacksonville, Florida, United States
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Publikationsverlauf

13. April 2015

28. Juni 2015

Publikationsdatum:
21. August 2015 (online)

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Abstract

Objectives Oncogenic osteomalacia is a paraneoplastic syndrome in which the tumor secretes a peptide-like hormone, fibroblast growth factor, resulting in urinary loss of phosphates.

Methods We present the case of a 50-year-old woman with a benign phosphaturic mesenchymal tumor (PMT) involving the ethmoid sinus with obstruction of the ostiomeatal complex causing unilateral nasal airway obstruction.

Results The tumor was initially thought to be an esthesioneuroblastoma based on primary pathology interpretation and on clinical and radiographic appearance. However, a benign PMT was later confirmed by further testing.

Conclusion The tumor was removed entirely by the endoscopic transnasal approach, leading to a full resolution of symptoms.

Keywords

phosphaturic mesenchymal tumor - skull base resection - endoscopic sinus surgery
 

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