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Synthesis 2016; 48(19): 3183-3198
DOI: 10.1055/s-0035-1562452
DOI: 10.1055/s-0035-1562452
paper
Diastereoselective Gold(I)-Catalyzed [2+2+2] Cycloaddition of Oxo-1,5-enynes
Weitere Informationen
Publikationsverlauf
Received: 21. Mai 2016
Accepted after revision: 13. Juni 2016
Publikationsdatum:
19. Juli 2016 (online)
![](https://www.thieme-connect.de/media/synthesis/201619/lookinside/thumbnails/ss-2016-c0371-op_10-1055_s-0035-1562452-1.jpg)
‡ These authors contributed equally.
In memory of Professor Jean Normant.
Abstract
The intramolecular gold(I)-catalyzed [2+2+2] cycloaddition of oxo-1,5-enynes bearing protected homopropargylic alcohols provides access to oxatricyclic adducts with good to excellent diastereoselectivity.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1562452.
- Supporting Information
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For reviews on the total synthesis of natural products using gold(I) catalysis, see:
See our previous reports on the total synthesis of terpenoids using gold(I) catalysis: