Described herein is a flexible modular approach to planar chiral carba-paracyclophanes via the stepwise assembly of two distinct side arms and the aromatic core followed by ring-closing olefin metathesis. Planar chirality is induced by one chiral sulfinyl group by forming a hydrogen bond to the phenol in the aromatic unit.
Key words
cyclophanes - paracyclophanes - planar chirality - atropisomerism - sulfoxides - hydrogen bond - metathesis