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Journal of Pediatric Neurology 2007; 05(04): 331-334
DOI: 10.1055/s-0035-1557403
Case Report
Georg Thieme Verlag KG Stuttgart – New York

Positron emission tomography imaging in a case of tuberous sclerosis and subependymal giant cell astrocytoma

Kutluhan Yilmaz
a   Department of Pediatrics Gaziantep University, Faculty of Medicine, Gaziantep, Turkiye
,
Mustafa Yilmaz
b   Department of Nuclear Medicine Gaziantep University, Faculty of Medicine, Gaziantep, Turkiye
,
Akif Sirikci
c   Department of Radiology Gaziantep University, Faculty of Medicine, Gaziantep, Turkiye
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Publication History

21 March 2007

23 May 2007

Publication Date:
30 July 2015 (online)

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Abstract

Positron emission tomography (PET), as a functional neuroimaging technique, provides biochemical and molecular information about brain and tumor tissues. We present the findings of FDG (2-deoxy-2[18F]-fluoro-D-glucose)-PET and magnetic resonance imaging in a 7-year-girl with tuberous sclerosis. Cranial magnetic resonance imaging revealed multiple cortical tubers, subependymal nodules and a subependymal giant cell astrocytoma. On FDG-PET images, the regions of cortical tubers were hypometabolic and the tumor also demonstrated hypometabolism implying a low-grade tumor. PET has been studied in tuberous sclerosis for many purposes including epilepsy and mental retardation. The present report suggests that FDG-PET could be useful in patients with tuberous sclerosis and intraventricular tumor as well.

Keywords

Tuberous sclerosis - positron emission tomography