A Brazilian sample of the red alga Laurencia nsp., yields sphingosines new to the marine environment

EM Stein; P Colepicolo; K Hagiwara; AD Wright

doi:10.1055/s-0035-1556336

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Planta Med 2015; 81 - PQ2
DOI: 10.1055/s-0035-1556336

A Brazilian sample of the red alga Laurencia nsp., yields sphingosines new to the marine environment

EM Stein ¹, P Colepicolo ¹, K Hagiwara ², AD Wright ²

¹Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508 – 900 São Paulo, Brazil
²DKI-College of Pharmacy, University of Hawaii at Hilo, 34 Rainbow Drive, Hilo, Hawaii 96720

Congress Abstract

Marine algae belonging to the genus Laurencia are the most prolific producers of secondary metabolites compared to any other marine genus. The secondary metabolites produced by these plants are typically halogenated and have a wide variety of biological properties. The most common structural classes encountered being sesquiterpenes, diterpenes, triterpenes, sterols, C₁₅ acetogenins and long-chain hydrocarbons. Sphingosines are among the lesser reported compounds isolated from this genus, with only one, (+)-N-(2S, 3R)-2-acetamido-3-acetoxyoctadecan-l-ol, being reported to date. In this poster presentation we report the isolation of additional sphingosines, including 1 and 2, from the genus Laurencia, this time from a new species collected in Brazil.