Download PDF
AJP Rep 2015; 05(02): e097-e098
DOI: 10.1055/s-0035-1548543
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Anatomical Closure of Left-to-Right Shunts in Premature Infants with Bronchopulmonary Dysplasia and Pulmonary Hypertension: A Cautionary Tale

Narendra R. Dereddy
1   Division of Neonatology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee
,
Sandeep R. Chilakala
1   Division of Neonatology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee
,
Divya Rana
1   Division of Neonatology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee
› Author Affiliations
Further Information

Publication History

02 September 2014

28 January 2015

Publication Date:
06 April 2015 (online)

Also available at
   Permissions and Reprints

Abstract

Closure of a systemic to pulmonary shunt in premature infants with bronchopulmonary dysplasia may be beneficial, but in the presence of pulmonary hypertension is controversial. Here, we discuss two premature infants with pulmonary hypertension who developed acute pulmonary hypertensive crisis after closure of these shunts and hence advise caution.

Keywords

premature - chronic lung disease - pulmonary hypertension - patent ductus arteriosus
 

  • References

  • 1 Baker CD, Abman SH, Mourani PM. Pulmonary Hypertension in Preterm Infants with Bronchopulmonary Dysplasia. Pediatr Allergy Immunol Pulmonol 2014; 27 (1) 8-16
    CrossrefPubMedGoogle Scholar
  • 2 An HS, Bae EJ, Kim GB , et al. Pulmonary hypertension in preterm infants with bronchopulmonary dysplasia. Korean Circ J 2010; 40 (3) 131-136
    CrossrefPubMedGoogle Scholar
  • 3 Bhat R, Salas AA, Foster C, Carlo WA, Ambalavanan N. Prospective analysis of pulmonary hypertension in extremely low birth weight infants. Pediatrics 2012; 129 (3) e682-e689
    CrossrefPubMedGoogle Scholar
  • 4 Keck EW. Pulmonaler Hochdruck und pulmonale Gefässerkrankung bei angeborenen Herzfehlern [in German]. Z Kardiol 1989; 78 (7) (Suppl. 07) 65-73
    PubMedGoogle Scholar
  • 5 Andrews R, Tulloh R, Magee A, Anderson D. Atrial septal defect with failure to thrive in infancy: hidden pulmonary vascular disease?. Pediatr Cardiol 2002; 23 (5) 528-530
    CrossrefPubMedGoogle Scholar
  • 6 Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001; 163 (7) 1723-1729
    CrossrefPubMedGoogle Scholar
  • 7 Bush A, Busst CM, Knight WB, Hislop AA, Haworth SG, Shinebourne EA. Changes in pulmonary circulation in severe bronchopulmonary dysplasia. Arch Dis Child 1990; 65 (7) 739-745
    CrossrefPubMedGoogle Scholar
  • 8 Abman SH, Wolfe RR, Accurso FJ, Koops BL, Bowman CM, Wiggins Jr JW. Pulmonary vascular response to oxygen in infants with severe bronchopulmonary dysplasia. Pediatrics 1985; 75 (1) 80-84
    PubMedGoogle Scholar
  • 9 Khemani E, McElhinney DB, Rhein L , et al. Pulmonary artery hypertension in formerly premature infants with bronchopulmonary dysplasia: clinical features and outcomes in the surfactant era. Pediatrics 2007; 120 (6) 1260-1269
    CrossrefPubMedGoogle Scholar
  • 10 Mourani PM, Sontag MK, Younoszai A, Ivy DD, Abman SH. Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease. Pediatrics 2008; 121 (2) 317-325
    CrossrefPubMedGoogle Scholar
  • 11 Flamant C, Hallalel F, Nolent P, Chevalier JY, Renolleau S. Severe respiratory syncytial virus bronchiolitis in children: from short mechanical ventilation to extracorporeal membrane oxygenation. Eur J Pediatr 2005; 164 (2) 93-98
    CrossrefPubMedGoogle Scholar
  • 12 Bhandari A, McGrath-Morrow S. Long-term pulmonary outcomes of patients with bronchopulmonary dysplasia. Semin Perinatol 2013; 37 (2) 132-137
    CrossrefPubMedGoogle Scholar
  • 13 Thomas VC, Vincent R, Raviele A, Diehl H, Qian H, Kim D. Transcatheter closure of secundum atrial septal defect in infants less than 12 months of age improves symptoms of chronic lung disease. Congenit Heart Dis 2012; 7 (3) 204-211
    CrossrefPubMedGoogle Scholar
  • 14 Niu MC, Mallory GB, Justino H, Ruiz FE, Petit CJ. Treatment of severe pulmonary hypertension in the setting of the large patent ductus arteriosus. Pediatrics 2013; 131 (5) e1643-e1649
    CrossrefPubMedGoogle Scholar
  • 15 del Cerro MJ, Sabaté Rotés A, Cartón A , et al. Pulmonary hypertension in bronchopulmonary dysplasia: clinical findings, cardiovascular anomalies and outcomes. Pediatr Pulmonol 2014; 49 (1) 49-59
    CrossrefPubMedGoogle Scholar