Planta Med 2015; 81(06): 436-449
DOI: 10.1055/s-0034-1396314
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Georg Thieme Verlag KG Stuttgart · New York

How to Valorize Biodiversity? Letʼs Go Hashing, Extracting, Filtering, Mining, Fishing

Quoc Tuan Do
1   Greenpharma S. A. S., Orléans, France
,
José L. Medina-Franco
2   Facultad de Química, Departamento de Farmacia, Universidad Nacional Autónoma de México, Mexico City, Mexico
,
Thomas Scior
3   Department of Pharmacy, Benemérita Universidad Autónoma de Puebla, Puebla, México
,
Philippe Bernard
1   Greenpharma S. A. S., Orléans, France
› Author Affiliations
Further Information

Publication History

received 15 July 2014
revised 21 October 2014

accepted 09 January 2015

Publication Date:
25 February 2015 (online)

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Abstract

Nature was and still is a prolific source of inspiration in pharmacy, cosmetics, and agro-food industries for the discovery of bioactive products. Informatics is now present in most human activities. Research in natural products is no exception. In silico tools may help in numerous cases when studying natural substances: in pharmacognosy, to store and structure the large and increasing number of data, and to facilitate or accelerate the analysis of natural products in regards to traditional uses of natural resources; in drug discovery, to rationally design libraries for screening natural compound mimetics and identification of biological activities for natural products. Here we review different aspects of in silico approaches applied to the research and development of bioactive substances and give examples of using nature-inspiring power and ultimately valorize biodiversity.

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