Download PDF
AJP Rep 2014; 04(02): e87-e88
DOI: 10.1055/s-0034-1390166
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Life-Threatening QT Prolongation in a Preterm Infant

Christian Paech
1   Department for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany
,
Roman Gebauer
1   Department for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany
,
Matthias Knüpfer
2   Department of Neonatology, University of Leipzig, Leipzig, Germany
› Author Affiliations
Further Information

Publication History

09 April 2014

25 July 2014

Publication Date:
10 November 2014 (online)

Also available at
   Permissions and Reprints

Abstract

Introduction Temporary QT-interval prolongation following intracranial hemorrhage and hydrocephalus has been repeatedly reported in adults.

Case We report a case of excessive QT prolongation with sudden bradycardia resulting in 2:1 atrioventricular conduction in a preterm infant most likely associated with a congenital hydrocephalus. Pathomechanisms are discussed.

Conclusion Congenital hydrocephalus predisposes to excessive QT prolongation in preterm infants.

Keywords

long QT - aqueductal stenosis - hydrocephalus - preterm
 

  • References

  • 1 Qaqa AY, Suleiman A, Alsumrain M, Debari VA, Kirmani J, Shamoon FE. Electrocardiographic abnormalities in patients presenting with intracranial parenchymal haemorrhage. Acta Cardiol 2012; 67 (6) 635-639
    PubMedGoogle Scholar
  • 2 van den Bergh WM, Algra A, Rinkel GJE. Electrocardiographic abnormalities and serum magnesium in patients with subarachnoid hemorrhage. Stroke 2004; 35 (3) 644-648
    CrossrefPubMedGoogle Scholar
  • 3 van Bree MD, Roos YB, van der Bilt IAC , et al. Prevalence and characterization of ECG abnormalities after intracerebral hemorrhage. Neurocrit Care 2010; 12 (1) 50-55
    CrossrefPubMedGoogle Scholar
  • 4 Cuneo BF, Etheridge SP, Horigome H , et al. Arrhythmia phenotype during fetal life suggests long-QT syndrome genotype: risk stratification of perinatal long-QT syndrome. Circ Arrhythm Electrophysiol 2013; 6 (5) 946-951
    CrossrefPubMedGoogle Scholar
  • 5 Uhrikova Z, Kolarovszki B, Javorka K , et al. Changes in heart rate variability in a premature infant with hydrocephalus. AJP Rep 2012; 2 (1) 43-46
    Article in Thieme ConnectPubMedGoogle Scholar