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DOI: 10.1055/s-0034-1387196
A Case of Stereotactic Radiation in Skull Base Solitary Fibrous Tumor: More Harm Than Good?
Publication History
15 March 2014
08 June 2014
Publication Date:
11 August 2014 (online)
![](https://www.thieme-connect.de/media/jnlsr/201402/lookinside/thumbnails/10.1055-s-0034-1387196-1.jpg)
Abstract
Objective Due to its location, total resection of a skull base solitary fibrous tumor (SFT) can lead to morbidity with injury to lower cranial nerves, and a decision must be made between subtotal resection with possible stereotactic radiotherapy or total resection with cranial nerve morbidity. We report the long-term outcomes and review the literature of a case of stereotactic radiation in SFT to provide evidence for making this decision.
Design A retrospective case review.
Setting An academic tertiary referral center.
Results We present a case with > 10 years follow-up of radiation following skull base SFT, initially misdiagnosed as schwannoma, where radiotherapy did not improve recurrence or metastatic behavior and led to complications during subsequent surgical resection.
Conclusions SFT often masquerades as schwannoma, especially in the skull base. Careful immunohistochemistry, including CD34 expression, is critical to the diagnosis and management. This case highlights that total tumor resection of SFT remains the gold standard of treatment. Stereotactic radiation is not recommended in the management of skull base SFT.
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References
- 1 Bisceglia M, Galliani C, Giannatempo G , et al. Solitary fibrous tumor of the central nervous system: a 15-year literature survey of 220 cases (August 1996-July 2011). Adv Anat Pathol 2011; 18 (5) 356-392
- 2 Deniz K, Kontas O, Tucer B, Kurtsoy A. Meningeal solitary fibrous tumor: report of a case and literature review. Folia Neuropathol 2005; 43 (3) 178-185
- 3 Ogawa K, Tada T, Takahashi S , et al. Malignant solitary fibrous tumor of the meninges. Virchows Arch 2004; 444 (5) 459-464
- 4 Gessi M, Gielen GH, Roeder-Geyer ED , et al. Extracranial metastasizing solitary fibrous tumors (SFT) of meninges: histopathological features of a case with long-term follow-up. Neuropathology 2013; 33 (1) 68-74
- 5 Milano MT, Singh DP, Zhang H. Thoracic malignant solitary fibrous tumors: a population-based study of survival. J Thorac Dis 2011; 3 (2) 99-104
- 6 Kawamura S, Nakamura T, Oya T , et al. Advanced malignant solitary fibrous tumor in pelvis responding to radiation therapy. Pathol Int 2007; 57 (4) 213-218
- 7 Nishioka H, Haraoka J, Ikeda Y. Risk factors of cerebrospinal fluid rhinorrhea following transsphenoidal surgery. Acta Neurochir (Wien) 2005; 147 (11) 1163-1166 ; discussion 1166
- 8 Zou WX, Leung TW, Yu SC , et al. Angiographic features, collaterals, and infarct topography of symptomatic occlusive radiation vasculopathy: a case-referent study. Stroke 2013; 44 (2) 401-406