Subscribe to RSS
![](/products/assets/desktop/img/oa-logo.png)
DOI: 10.1055/s-0034-1387189
Solitary Osteochondroma of the Skull Base: A Case Report and Literature Review
Publication History
20 March 2014
30 June 2014
Publication Date:
02 March 2015 (online)
![](https://www.thieme-connect.de/media/jnlsr/201501/lookinside/thumbnails/10-1055-s-0034-1387189_140023-1.jpg)
Abstract
We report a case of an osteochondroma in the posterior clinoid process that occurred in a 43-year-old man with trochlear nerve palsy. Although the potential preoperative diagnoses based on computed tomography and magnetic resonance imaging included other intracranial tumors such as calcified meningioma, thallium-201 single-photon emission computed tomography effectively differentiated osteochondroma from those possibilities. Via an orbitozygomatic approach, a subtotal resection was achieved with a good relief of symptoms. Twenty-two cases of solitary osteochondromas in the skull base have been reported that have demonstrated little risk of recurrence or malignant transformation. However, surgery for skull base osteochondromas does carry a significant risk with a reported mortality > 10%. Although some previous reports advocate complete resection as the only curative method for skull base osteochondromas, the risks of total resection should be weighed against the chance for recurrence; our review of the literature demonstrated a relatively high mortality and an extremely low incidence of recurrence.
-
References
- 1 Somerset HL, Kleinschmidt-DeMasters BK, Rubinstein D, Breeze RE. Osteochondroma of the convexity: pathologic-neuroimaging correlates of a lesion that mimics high-grade meningioma. J Neurooncol 2010; 98 (3) 421-426
- 2 Murphey MD, Choi JJ, Kransdorf MJ, Flemming DJ, Gannon FH. Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics 2000; 20 (5) 1407-1434
- 3 Beck DW, Dyste GN. Intracranial osteochondroma: MR and CT appearance. AJNR Am J Neuroradiol 1989; 10 (5, Suppl): S7-S8
- 4 Bonde V, Srikant B, Goel A. Osteochondroma of basi-occiput. Neurol India 2007; 55 (2) 182-183
- 5 Crawford SC, Cornell SH, Franken EA. General case of the day. Intracranial osteochondroma. Radiographics 1987; 7 (6) 1178-1180
- 6 Forsythe RW, Baker GS , et al. Intracranial osteochondroma. Proc Staff Meet Mayo Clin 1947; 22 (17) 350-356
- 7 Haddad GF, Haddad FS, Zaatari G. Dural osteochondroma: case report, review of the literature and proposal of a new classification. Br J Neurosurg 1998; 12 (4) 380-384
- 8 Hatayama T, Sekiya T, Suzuki S, Iwabuchi T. A case of intracranial osteochondroma: its MR images [in Japanese]. No Shinkei Geka 1989; 17 (11) 1063-1066
- 9 Herskowitz A, el-Gammal T. Supratentorial cartilaginous tumors. (A report of 2 cases). Dis Nerv Syst 1973; 34 (7) 384-388
- 10 Himuro H, Suzuki H, Takeyama E, Jinbo M, Kitamura K. A case of intracranial osteochondroma [in Japanese]. No Shinkei Geka 1977; 5 (10) 1079-1083
- 11 Ikeda Y, Shimura T, Higuchi H, Nakazawa S, Sugisaki Y. Intracranial osteochondroma—case report [in Japanese]. No Shinkei Geka 1980; 8 (3) 263-269
- 12 Inoue T, Takahashi N, Murakami K, Nishimura S, Kaimori M, Nishijima M. Osteochondroma of the sella turcica presenting with intratumoral hemorrhage. Neurol Med Chir (Tokyo) 2009; 49 (1) 37-41
- 13 Ito U, Hashimoto K, Inaba Y. Osteochondroma of the posterior clinoid process. Report of a case with special reference to its histogenesis. Acta Neuropathol 1974; 27 (4) 329-335
- 14 Lin WC, Lirng JF, Ho DMT , et al. A rare giant intracranial osteochondroma. Zhonghua Yi Xue Za Zhi (Taipei) 2002; 65 (5) 235-238
- 15 Lotfinia I, Vahedi P, Tubbs RS, Gavame M, Vahedi A. Basioccipital bone osteochondroma growing into the foramen magnum. Surg Neurol Int 2012; 3: 21
- 16 Mashiyama S, Sakurai Y, Kayama T, Nishino A, Jokura H. A case of intracranial osteochondroma originating with psychomotor epilepsy [in Japanese]. No Shinkei Geka 1994; 22 (2) 165-168
- 17 Matz S, Israeli Y, Shalit MN, Cohen ML. Computed tomography in intracranial supratentorial osteochondroma. J Comput Assist Tomogr 1981; 5 (1) 109-115
- 18 Nagai S, Yamamoto N, Wakabayashi K , et al. Osteochondroma arising from the convexity dura mater. Case illustration. J Neurosurg 1998; 88 (3) 610
- 19 Omalu BI, Wiley CA, Hamilton RL. February 2003: a 53-year-old male with new onset seizures. Brain Pathol 2003; 13 (3) 419-420 , 423
- 20 Richards WW, Thompson MC. Suprasellar osteochondroma with chiasmal syndrome. Arch Ophthalmol 1961; 65: 437-441
- 21 Sato K, Kodera T, Kitai R, Kubota T. Osteochondroma of the skull base: MRI and histological correlation. Neuroradiology 1996; 38 (1) 41-43
- 22 Venkata RI, Kakarala SV, Garikaparthi S, Duttaluru SS, Parvatala A, Chinnam A. Giant intracranial osteochondroma: a case report and review of the literature. Surg Neurol Int 2011; 2: 118
- 23 Yamaguchi T, Wada S, Matsukado Y. Intracranial giant osteochondroma with unusual clinical features [in Japanese]. No Shinkei Geka 1983; 11 (2) 181-184
- 24 Bakdash H, Alksne JF, Rand RW. Osteochondroma of the base of the skull causing an isolated oculomotor nerve paralysis. Case report emphasizing microsurgical techniques. J Neurosurg 1969; 31 (2) 230-233
- 25 Fon G, Sage MR. Osteochondroma of the clivus. Australas Radiol 1979; 23 (1) 46-53
- 26 Alpers BJ. Cerebral osteochondroma of dural origin. Ann Surg 1935; 101 (1) 27-37
- 27 Bovée JV, Hogendoorn PCW. Multiple osteochondromas. In World Health Organization classification of tumours. Pathology and genetics of tumours of soft tissue and bone. Edited by: Fletcher CDM, Unni KK and Mertens F. Lyon, IARC Press; 2002; 360-362