Monoterpenoid Coumarins from the Peels of Clausena lansium

Hui-Dong Deng; Wen-Li Mei; Zhi-Kai Guo; Shuai Liu; Wen-Jian Zuo; Wen-Hua Dong; Shao-Peng Li; Hao-Fu Dai

doi:10.1055/s-0034-1382839

Planta Medica, Inhaltsverzeichnis

Planta Med 2014; 80(11): 955-958
DOI: 10.1055/s-0034-1382839

Natural Product Chemistry

Letters

Georg Thieme Verlag KG Stuttgart · New York

Monoterpenoid Coumarins from the Peels of Clausena lansium

Hui-Dong Deng^*

¹Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China

²Key Laboratory of Protection and Developmental Utilization of Tropical Crop Germplasm Resources, Ministry of Education, College of Horticulture and Landscape Architecture, Hainan University, Haikou, Hainan, P. R. China

,

Wen-Li Mei^*

¹Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China

,

Zhi-Kai Guo

¹Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China

,

Shuai Liu

¹Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China

,

Wen-Jian Zuo

¹Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China

,

Wen-Hua Dong

¹Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China

,

Shao-Peng Li

²Key Laboratory of Protection and Developmental Utilization of Tropical Crop Germplasm Resources, Ministry of Education, College of Horticulture and Landscape Architecture, Hainan University, Haikou, Hainan, P. R. China

,

Hao-Fu Dai

¹Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture (Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine), Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China

› Institutsangaben

Abstract

A phytochemical investigation on the peels of Clausena lansium (Lour.) Skeels led to the isolation of two new monoterpenoid coumarins, named clauslactone V (1) and clauslactone W (2), together with three known analogues (3–5). Their structures were elucidated by spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). All the compounds were evaluated for hypoglycemic activity, and compounds 1–5 showed α-glucosidase inhibitory activity in vitro.

Key words

Clausena lansium - Rutaceae - monoterpenoid coumarins - clauslactone V - clauslactone W - hypoglycemic activity

Volltext

Referenzen

References
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