Two new flavone glycosides from Chenopodium ambrosioides growing wildly in Egypt

HM Hammoda; MM Radwan; FM Harraz; MG Al Ghazouly; MA ElSohly; AS Wanas; SM Bassam

doi:10.1055/s-0034-1382488

Planta Medica, Table of Contents

Two new flavone glycosides from Chenopodium ambrosioides growing wildly in Egypt

HM Hammoda ¹, MM Radwan ¹^,², FM Harraz ¹, MG Al Ghazouly ¹^,³, MA ElSohly ²^,⁴, AS Wanas ²^,⁵, SM Bassam ³

¹Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt
³Department of Pharmacognosy, Faculty of Pharmacy, Pharos University, Egypt
²National Center for Natural Products Research
⁴Department of Pharmaceutics, School of pharmacy, University of Mississippi, University MS 38655, USA
⁵Pharmacognosy Department, Faculty of Pharmacy, University of Minia, Egypt

Abstract

Extract of the aerial parts of Chenopodium ambrosioides (Chenopodiaceae) growing wildly in Egypt was subjected to antioxidant-guided fractionation. The ethyl acetate fraction was found to be the most active fraction. Further phytochemical investigation of this fraction afforded two new flavone glycosides; scutellarein-7-O-rhamnosyl (1→2) rhamnosyl (1→2) rhamnoside 1 and scutellarein-7-O-rhamnosyl (1→2) rhamnoside 2. In addition, the in vitro antioxidant activities of the total alcoholic extract, ethyl acetate and chloroformic fractions of the plant and isolates were studied.

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