Primary Intracranial Leiomyosarcoma- Case Report and Review of the Literature

Intracranial neoplasms of mesenchymal origin are uncommon. Primary intracranial soft tissue sarcomas can arise from mesenchymal cells of the dura matter or of the cerebral blood vessels. We reported a 30-year-old man presented with a 1-month history of a progressive headache with nausea and disturbed consciousness in the day of hospitalization. A CT scan demonstrated a large tumor arising from the frontal part of the cerebral falx, primary suspected for falx meningioma. Intraoperatively, the tumor was with extensive blood supply from abnormal large vessels and was destructing the falx. The histopathologic analysis of the intracranial mass was consistent with leiomyosarcoma. Whole body CT did not reveal metastatic tumors. Two months after the total tumor removal the control CT examination revealed tumor regrowth with similar volume. Primary intracranial leiomyosarcomas are rare tumors. Imaging diagnosis could not be conclusive. Current therapeutic approaches appear to have limited benefits and, as a rule the outcome is poor.