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Synlett 2014; 25(13): 1904-1908
DOI: 10.1055/s-0034-1378331
letter
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Mono- and Diaza-‘Pyridones’ via Stille Coupling of Alkoxystannanes

Charlotte L. Smith
School of Chemistry, University of Bristol, Bristol BS8 1TS, UK   Fax: +44(117)9298611   Email: t.gallagher@bristol.ac.uk
,
Christoph Hirschhäuser
School of Chemistry, University of Bristol, Bristol BS8 1TS, UK   Fax: +44(117)9298611   Email: t.gallagher@bristol.ac.uk
,
Georgia K. Malcolm
School of Chemistry, University of Bristol, Bristol BS8 1TS, UK   Fax: +44(117)9298611   Email: t.gallagher@bristol.ac.uk
,
Daniel J. Nasrallah
School of Chemistry, University of Bristol, Bristol BS8 1TS, UK   Fax: +44(117)9298611   Email: t.gallagher@bristol.ac.uk
,
Timothy Gallagher*
School of Chemistry, University of Bristol, Bristol BS8 1TS, UK   Fax: +44(117)9298611   Email: t.gallagher@bristol.ac.uk
› Author Affiliations
Further Information

Publication History

Received: 02 May 2014

Accepted after revision: 23 May 2014

Publication Date:
08 July 2014 (online)

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Abstract

Various alkoxy-substituted heterocyclic stannanes provide access to the corresponding substituted ‘pyridone’ moieties via Stille cross-coupling. Both pyridyl and a series of diazinyl stannanes are prepared, and options for unmasking (via demethylation or debenzylation) of the pyridone unit are evaluated.

Key words

pyridine - heterocyclic stannane - Stille coupling
 

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