Synlett 2014; 25(13): 1939-1940
DOI: 10.1055/s-0034-1378326
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© Georg Thieme Verlag Stuttgart · New York

New Uses for Indium(III) Chloride

Rosana Helena C. N. Freitas
LASSBio, B16, CCS, Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, Brazil   Email: rosanahf@iq.ufrj.br
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Publication History

Publication Date:
01 July 2014 (online)

Introduction

Indium(III) chloride (InCl3) is an inexpensive, commercially available, easy-to-handle, air- and water-stable Lewis acid with moderate toxicity. It shows a high tolerance to most functional groups including oxygen and ­nitrogen functionalities.[1] Additionally, InCl3 is very attractive for green-chemistry reactions due to its recyclability.[2] Therefore, InCl3 has been described as a catalyst for various reactions, especially multicomponent reactions (MCR),[3] as given below.