PDF herunterladen
Int J Angiol 2016; 25(05): e8-e11
DOI: 10.1055/s-0034-1376397
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Ergotism: Case Report and Review of the Literature

Claudia A. Liegl
1   Vascular Laboratory, St Vincent's Clinic, Darlinghurst, Sydney, New South Wales, Australia
,
Michael A. McGrath
1   Vascular Laboratory, St Vincent's Clinic, Darlinghurst, Sydney, New South Wales, Australia
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
09. Februar 2015 (online)

    Lizenzen und Reprints

Abstract

A case of ergotism is presented to illustrate the role of duplex ultrasonography in the diagnosis and management of this nonatherosclerotic cause of peripheral arterial disease. Historical aspects of ergotism are discussed together with reference to the relative vulnerability of different segments of the arterial circulation. Our case emphasizes the potential for complete reversibility of the vascular changes if recognized early.

Keywords

ergotism - ergot alkaloids - Claviceps purpurea - nonatherosclerotic arterial disease - lower limb ischemia - migraine - duplex ultrasound
 

  • References

  • 1 Tribble MA, Gregg CR, Margolis DM, Amirkhan R, Smith JW. Fatal ergotism induced by an HIV protease inhibitor. Headache 2002; 42 (7) 694-695
    PubMedGoogle Scholar
  • 2 Enge I, Sivertssen E. Ergotism due to therapeutic doses of ergotamine tartrate. Am Heart J 1965; 70 (5) 665-670
    CrossrefPubMedGoogle Scholar
  • 3 Kelbessa U, Asfaw D, Yeshi W, Agata N, Abebe B, Wubalem Z. Laboratory studies on the outbreak of Gangrenous Ergotism associated with consumption of contaminated barley in Arsi, Ethiopia. Ethiop J Health Dev 2002; 16 (3) 317-323
    PubMedGoogle Scholar
  • 4 Lee MR. The history of ergot of rye (Claviceps purpurea) I: from antiquity to 1900. J R Coll Physicians Edinb 2009; 39 (2) 179-184
    PubMedGoogle Scholar
  • 5 Schiff PL. Ergot and its alkaloids. Am J Pharm Educ 2006; 70 (5) 98
    CrossrefPubMedGoogle Scholar
  • 6 Baldwin ZK, Ceraldi CC. Ergotism associated with HIV antiviral protease inhibitor therapy. J Vasc Surg 2003; 37 (3) 676-678
    CrossrefPubMedGoogle Scholar
  • 7 Garcia GD, Goff Jr JM, Hadro NC, O'donnell SD, Greatorex PS. Chronic ergot toxicity: A rare cause of lower extremity ischemia. J Vasc Surg 2000; 31 (6) 1245-1247
    CrossrefPubMedGoogle Scholar
  • 8 Merhoff GC, Porter JM. Ergot intoxication: historical review and description of unusual clinical manifestations. Ann Surg 1974; 180 (5) 773-779
    CrossrefPubMedGoogle Scholar
  • 9 Zavaleta EG, Fernandez BB, Grove MK, Kaye MD. St. Anthony's fire (ergotamine induced leg ischemia)—a case report and review of the literature. Angiology 2001; 52 (5) 349-356
    CrossrefPubMedGoogle Scholar
  • 10 Cagatay A, Guler O, Guven K. Ergotism caused by concurrent use of ritonavir and ergot alkaloids: a case report. Acta Chir Belg 2009; 109 (5) 639-640
    PubMedGoogle Scholar
  • 11 Bagby RJ, Cooper RD. Angiography in ergotism. Report of two cases and review of the literature. Am J Roentgenol Radium Ther Nucl Med 1972; 116 (1) 179-186
    CrossrefPubMedGoogle Scholar
  • 12 Fagerberg S, Jorulf H, Sandberg CG. Ergotism, arteriospastic disease and recovery, studied angiographically. Acta Med Scand 1967; 182 (6) 769-772
    PubMedGoogle Scholar
  • 13 Venter CP, Joubert PH, Buys AC. Severe peripheral ischaemia during concomitant use of beta blockers and ergot alkaloids. Br Med J (Clin Res Ed) 1984; 289 (6440) 288-289
    PubMedGoogle Scholar
  • 14 Weaver R, Phillips M, Vacek JL. St. Anthony's fire: a medieval disease in modern times: case history. Angiology 1989; 40 (10) 929-932
    CrossrefPubMedGoogle Scholar
  • 15 Goldfisher JD. Acute myocardial infarction secondary to ergot therapy. N Engl J Med 1960; 262: 860-863
    CrossrefPubMedGoogle Scholar
  • 16 Mathey D, Montz R, Hanrath P, Kuck KH, Bleifeld W. Noninvasive method for recognition of coronary artery spasm: 201thallium sequential scintigraphy of themyocardium after ergotamine provocation (author's translation). (in English). Dtsch Med Wochenschr 1980; 105 (15) 509-515
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 17 Byrne-Quinn E. Arteriospasm after overdose of oral ergotamine tartrate in migraine. BMJ 1964; 2 (5408) 552-553
    CrossrefPubMedGoogle Scholar
  • 18 Ellison ABC. Ergot intoxication in a young woman with migraine (case report). W V Med J 1960; 56: 376-379
    PubMedGoogle Scholar
  • 19 Lazarides MK, Karageorgiou C, Tsiara S, Grillia M, Dayantas JN. Severe facial ischaemia caused by ergotism. J Cardiovasc Surg (Torino) 1992; 33 (3) 383-385
    PubMedGoogle Scholar
  • 20 Richter AM, Banker VP. Carotid ergotism. A complication of migraine therapy. Radiology 1973; 106 (2) 339-340
    CrossrefPubMedGoogle Scholar
  • 21 Fedotin MS, Hartman C. Ergotamine poisoning producing renal arterial spasm. N Engl J Med 1970; 283 (10) 518-520
    CrossrefPubMedGoogle Scholar
  • 22 Greene FL, Ariyan S, Stansel Jr HC. Mesenteric and peripheral vascular ischemia secondary to ergotism. Surgery 1977; 81 (2) 176-179
    PubMedGoogle Scholar
  • 23 Hemingway DL. Ergot poisoning with multisystem involvement. Mil Med 1965; Nov 130 (11) 1103-1106
    CrossrefPubMedGoogle Scholar
  • 24 Demir S, Akin S, Tercan F, Ariboğan A, Oğuzkurt L. Ergotamine-induced lower extremity arterial vasospasm presenting as acute limb ischemia. Diagn Interv Radiol 2010; 16 (2) 165-167
    PubMedGoogle Scholar
  • 25 Fischer GM, Llaurado JG. Collagen and elastin content in canine arteries selected from functionally different vascular beds. Circ Res 1966; 19 (2) 394-399
    CrossrefPubMedGoogle Scholar
  • 26 Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs. Circ Res 2002; 90 (7) 826-832
    CrossrefPubMedGoogle Scholar