Autoinflammatory Diseases (AID)

Abstract

Most of the autoinflammatory diseases (AID) are orphan diseases with recurrent episodes of systemic inflammation. Fever and exanthema are leading features. Given the ongoing elucidation of pathogenic causes and hence therapeutic approaches, we provided a review of the current literature of AID.

Zusammenfassung

Die meisten autoinflammatorischen Erkrankungen sind seltene Erkrankungen mit wiederk­eh­renden Episoden systemischer Inflammation. Fieber und Exanthem sind führende Merkmale. In Anbetracht der fortlaufenden Aufklärung pathogenetischer Ursachen und der daraus resultierenden Therapieansätze, stellen wir die gegenwärtige Literatur über AID zusammenfassend dar.

Key words

autoinflammatory diseases - monogenetic - inflammasome - interleukin 1

Schlüsselwörter

Autoinflammation - monogenetische Erkrankungen - Inflammasom - Interleukin 1

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