Elektrochemotherapie zur Behandlung von Hauttumoren und Hautmetastasen

Zusammenfassung

Nach Ausschöpfung von klassischen Behandlungsverfahren wie Chemo- und Strahlentherapie gibt es für Patienten mit ausgedehnten, inoperablen Hauttumoren oder Hautmetastasen nur wenige Möglichkeiten einer lokalen Tumorkontrolle. Die Elektrochemotherapie bietet in diesen Fällen eine hocheffektive, nebenwirkungsarme Behandlungsoption, die wiederholt auch in vorbehandelten Arealen und ohne wesentliche Einschränkungen im Hinblick auf Anzahl und Lage der Metastasen eingesetzt werden kann. Durch die Reduktion der Tumormasse sowie Minderung etwaiger Blutungen und Exsudation kann eine deutliche Verbesserung der Lebensqualität für die betroffenen Patienten erzielt werden. Der Erfolg der Elektrochemotherapie gibt aktuell Anlass zur Überprüfung der Indikationserweiterung auf viszerale Tumore, Knochenmetastasen und sogar Hirntumore.

Abstract

Following classic treatment options for cancer patients such as chemotherapy or radiation, only few therapies remain for patients with widespread, inoperable skin tumours or metastases. Electrochemotherapy is a highly effective treatment approach in such cases with few side effects. Electrochemotherapy can be repeatedly performed even in pre-treated areas without substantial limitations concerning number and location of skin metastases. Reduction of tumor mass and decrease of bleeding and exudation might significantly improve patient’s quality of live. The overall success of electrochemotherapy encourages expanding its indication to visceral tumours or bone and brain metastases.

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