Download PDF
Int Arch Otorhinolaryngol 2015; 19(01): 093-095
DOI: 10.1055/s-0033-1353368
Case Report
Thieme Publicações Ltda Rio de Janeiro, Brazil

Isolated Schwannoma of the Olfactory Groove: A Case Report

Luiz Augusto Nascimento
1   Division of Skull Base Surgery, Department of Otolaryngology–Head and Neck Surgery, Universidade Federal de São Paulo, São Paulo/SP, Brazil
,
Flávio Aurélio Parente Settanni
1   Division of Skull Base Surgery, Department of Otolaryngology–Head and Neck Surgery, Universidade Federal de São Paulo, São Paulo/SP, Brazil
,
José Franscisco de Góis Filho
2   Department of Head and Neck Surgery, Instituto do Cancêr Arnaldo Vieira de Carvalho, São Paulo/SP, Brazil
,
Isabela Naria Dias Sanchez
3   Department of Oncology, Universidade Federal de São Paulo, São Paulo/SP, Brazil
,
Bruna Barros Cavalcante
4   Department of Head and Neck Surgery, Universidade de Brasília, Brasília/DF, Brazil
,
João Noberto Stávale
5   Department of Pathology, Universidade Federal de São Paulo, São Paulo/SP, Brazil
› Author Affiliations
Further Information

Publication History

06 February 2013

01 July 2013

Publication Date:
05 November 2013 (online)

Also available at
   Permissions and Reprints

Abstract

Introduction Schwannoma of the olfactory groove is an extremely rare tumor that can share a differential diagnosis with meningioma or neuroblastoma.

Objectives The authors present a case of giant schwannoma involving the anterior cranial fossa and ethmoid sinuses.

Case Report The patient presented with a 30-month history of left nasal obstruction, anosmia, and sporadic ipsilateral bleeding. Computed tomography of the paranasal sinuses revealed expansive lesion on the left nasal cavity extending to nasopharynx up to ethmoid and sphenoid sinuses bilaterally with intraorbital and parasellar extension to the skull base. Magnetic resonance imaging scan confirmed the expansive tumor without dural penetration. Biopsy revealed no evidence of malignancy and probable neural cell. Bifrontal craniotomy was performed combined with lateral rhinotomy (Weber-Ferguson approach), and the lesion was totally removed. The tumor measured 8.0 × 4.3 × 3.7 cm and microscopically appeared as a schwannoma composed of interwoven bundles of elongated cells (Antoni A regions) mixed with less cellular regions (Antoni B). Immunohistochemical study stained intensively for vimentin and S-100.

Conclusion Schwannomas of the olfactory groove are extremely rare, and the findings of origin of this tumor is still uncertain but recent studies point most probably to the meningeal branches of trigeminal nerve or anterior ethmoidal nerves.

Keywords

paranasal sinuses - skull base - neurilemmoma - olfactory nerve - head and neck neoplasms - neoplasms - nerve tissue
 

  • References

  • 1 Auer RN, Budny J, Drake CG, Ball MJ. Frontal lobe perivascular schwannoma. Case report. J Neurosurg 1982; 56 (1) 154-157
    CrossrefPubMedGoogle Scholar
  • 2 Gibson AA, Hendrick EB, Conen PE. Case reports. Intracerebral schwannoma. Report of a case. J Neurosurg 1966; 24 (2) 552-557
    CrossrefGoogle Scholar
  • 3 Ramamurthy B, Anguli V, Iyer CGS. A case of intramedullary neurinoma. J Neurosurg 1958; 27: 92-94
    Google Scholar
  • 4 Redekop G, Elisevich K, Gilbert J. Fourth ventricular schwannoma. Case report. J Neurosurg 1990; 73 (5) 777-781
    CrossrefGoogle Scholar
  • 5 Amador AR, Santonja C, Del Pozo JM, Ortiz L. Olfactory schwannoma. Eur Radiol 2002; 12 (4) 742-744
    CrossrefGoogle Scholar
  • 6 Sturm KW, Bonis G, Kosmaoglu V. [On a neurinoma of the cribriform lamina]. Zentralbl Neurochir 1968; 29 (4) 217-222
    PubMedGoogle Scholar
  • 7 Figueiredo EG, Soga Y, Amorim RL, Oliveira AM, Teixeira MJ. The puzzling olfactory groove schwannoma: a systematic review. Skull Base 2011; 21 (1) 31-36
    Article in Thieme ConnectPubMedGoogle Scholar
  • 8 Choi YS, Sung KS, Song YJ, Kim HD. Olfactory schwannoma-case report-. J Korean Neurosurg Soc 2009; 45 (2) 103-106
    CrossrefGoogle Scholar
  • 9 Bezircioğlu H, Sucu HK, Rezanko T, Minoğlu M. Nasal-subfrontal giant schwannoma. Turk Neurosurg 2008; 18 (4) 412-414
    Google Scholar
  • 10 Sano H, Hayashi Y, Hasegawa M, Yamashita J. Subfrontal schwannoma without hyposmia—case report. Neurol Med Chir (Tokyo) 2004; 44 (11) 591-594
    CrossrefGoogle Scholar
  • 11 Nagao S, Aoki T, Kondo S, Gi H, Matsunaga M, Fujita Y. [Subfrontal schwannoma: a case report]. No Shinkei Geka 1991; 19 (1) 47-51
    Google Scholar
  • 12 Sato S, Toya S, Nakamura T , et al. [Subfrontal schwannoma: report of a case]. No Shinkei Geka 1985; 13 (8) 883-887
    Google Scholar
  • 13 Husain M, Mishra UK, Newton G, Husain N. Isolated olfactory groove neurilemmoma. Surg Neurol 1992; 37 (2) 115-117
    CrossrefGoogle Scholar
  • 14 Sabel LH, Teepen JL. The enigmatic origin of olfactory schwannoma. Clin Neurol Neurosurg 1995; 97 (2) 187-191
    CrossrefGoogle Scholar
  • 15 Adachi K, Yoshida K, Miwa T, Ikeda E, Kawase T. Olfactory schwannoma. Acta Neurochir (Wien) 2007; 149 (6) 605-610 , discussion 610–611
    CrossrefPubMedGoogle Scholar
  • 16 Saberi H, Khashayar P. Olfactory groove schwannoma masquerading as an orbital mass. Neurosciences (Riyadh) 2008; 13 (1) 73-76
    Google Scholar
  • 17 Frim DM, Ogilvy CS, Vonsattal JP, Chapman PH. Is intracerebral schwannoma a developmental tumor of children and young adults? Case report and review. Pediatr Neurosurg 1992; 18 (4) 190-194
    CrossrefPubMedGoogle Scholar
  • 18 Huang PP, Zagzag D, Benjamin V. Intracranial schwannoma presenting as a subfrontal tumor: case report. Neurosurgery 1997; 40 (1) 194-197
    CrossrefGoogle Scholar
  • 19 Yasuda M, Higuchi O, Takano S, Matsumura A. Olfactory ensheathing cell tumor: a case report. J Neurooncol 2006; 76 (2) 111-113
    CrossrefPubMedGoogle Scholar
  • 20 Mirone G, Natale M, Scuotto A, Rotondo M. Solitary olfactory groove schwannoma. J Clin Neurosci 2009; 16 (3) 454-456
    CrossrefPubMedGoogle Scholar
  • 21 Martínez-Soto L, Alfaro-Baca R, Torrecilla-Sardón MV, Fernández-Vallejo B, Ferreira-Muñóz R, De Diego T. [A new case of “olfactory schwannoma”; presentation and literature review]. Neurocirugia (Astur) 2009; 20 (3) 294-297
    Google Scholar
  • 22 Kanaan HA, Gardner PA, Yeaney G , et al. Expanded endoscopic endonasal resection of an olfactory schwannoma. J Neurosurg Pediatr 2008; 2 (4) 261-265
    CrossrefPubMedGoogle Scholar
  • 23 Daglioglu E, Okay O, Dalgic A, Albayrak AL, Ergungor F. Cystic olfactory schwannoma of the anterior cranial base. Br J Neurosurg 2008; 22 (5) 697-699
    CrossrefGoogle Scholar
  • 24 Yako K, Morita A, Ueki K, Kirino T. Subfrontal schwannoma. Acta Neurochir (Wien) 2005; 147 (6) 655-657 , discussion 657–658
    CrossrefGoogle Scholar
  • 25 Komoribayashi N, Arai H, Kojo T, Obonai C, Wakabayashi J, Ogawa A. [Subfrontal schwannoma: case report]. No Shinkei Geka 2005; 33 (6) 601-605
    Google Scholar
  • 26 Prasad D, Jalali R, Shet T. Intracranial subfrontal schwannoma treated with surgery and 3D conformal radiotherapy. Neurol India 2004; 52 (2) 248-250
    Google Scholar
  • 27 Shenoy SN, Raja A. Cystic olfactory groove schwannoma. Neurol India 2004; 52 (2) 261-262
    PubMedGoogle Scholar
  • 28 Murakami M, Tsukahara T, Hatano T, Nakakuki T, Ogino E, Aoyama T. Olfactory groove schwannoma—case report. Neurol Med Chir (Tokyo) 2004; 44 (4) 191-194
    CrossrefPubMedGoogle Scholar
  • 29 Yuen A, Trost N, McKelvie P, Webster J, Murphy M. Subfrontal schwannoma: a case report and literature review. J Clin Neurosci 2004; 11 (6) 663-665
    CrossrefPubMedGoogle Scholar
  • 30 de Souza HL, Ramos AM, Ramos CC , et al. [Olfactory groove schwannoma: case report]. Arq Neuropsiquiatr 2003; 61 (1) 125-128
    CrossrefGoogle Scholar
  • 31 Carron JD, Singh RV, Karakla DW, Silverberg M. Solitary schwannoma of the olfactory groove: case report and review of the literature. Skull Base 2002; 12 (3) 163-166
    CrossrefGoogle Scholar
  • 32 Tsai YD, Lui CC, Eng HL, Liang CL, Chen HJ. Intracranial subfrontal schwannoma. Acta Neurochir (Wien) 2001; 143 (3) 313-314
    CrossrefGoogle Scholar
  • 33 Ahmad FU, Gupta A, Sharma MC, Shukla G, Mehta VS. The enigmatic origin of subfrontal schwannomas: report of a case without hyposmia. Acta Neurochir (Wien) 2006; 148 (6) 671-672 , discussion 672
    CrossrefPubMedGoogle Scholar
  • 34 Bando K, Obayashi M, Tsuneharu F. [A case of subfrontal schwannoma]. No Shinkei Geka 1992; 20 (11) 1189-1194
    Google Scholar
  • 35 Russell DS, Rubinstein LJ. Pathology of Tumors of the Nervous System. 3rd ed. London, UK: Edward Arnold; 1971: 286
    Google Scholar
  • 36 Ulrich J, Lévy A, Pfister C. Schwannoma of the olfactory groove. Case report and review of previous cases. Acta Neurochir (Wien) 1978; 40 (3-4) 315-321
    CrossrefGoogle Scholar
  • 37 Ben Rhouma T, Bouzakoura C, Boudaouara MA, Mhiri C, Hentati K. [Intracerebral schwannoma. Apropos of a case]. Neurochirurgie 1988; 34 (2) 123-127
    Google Scholar
  • 38 Ghatak NR, Norwood CW, Davis CH. Intracerebral schwannoma. Surg Neurol 1975; 3 (1) 45-47
    Google Scholar
  • 39 Kasantikul V, Brown WJ, Cahan LD. Intracerebral neurilemmoma. J Neurol Neurosurg Psychiatry 1981; 44 (12) 1110-1115
    CrossrefGoogle Scholar
  • 40 Vassilouthis J, Richardson AE. Subfrontal schwannoma. Report of a case. Acta Neurochir (Wien) 1980; 53 (3-4) 259-266
    CrossrefGoogle Scholar
  • 41 Li YP, Jiang S, Zhou PZ, Ni YB. Solitary olfactory schwannoma without olfactory dysfunction: a new case report and literature review. Neurol Sci 2012; 33 (1) 137-142
    PubMedGoogle Scholar
  • 42 Viale ES, Pau A, Turtal S. Olfactory groove neurinomas. J Neurosurg Sci 1973; 17: 193-196
    Google Scholar