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DOI: 10.1055/s-0033-1352231
New flavonoid glucoside and other components taken from Filipendula genus plants
The meadowsweet (Filipendula ulmaria Maxim.) is widely using plant in herbal medicine. Phenolics are one of the most important groups of nature compounds defining a pharmacological action of F. ulmaria. At the same time there are other widespread plants of Filipendula genus which can be used as a source of herbal medicines. The research of a chemical structure of these plants is necessary for identification of close species within the Filipendula genus.
The separation of extract taken from F. ulmaria shoots was conducted by chromatographic methods. As a result forty nine substances were isolated including 48 known and a new compound named ulmarioside. Investigation of ulmarioside by complex of spectral methods (UV, IR, MS, NMR) allow to describe its structure as a quercetin-4′-O-α-rhamnopyranosyl-(1 – 6)-β-glucopyranoside (quercetin-4′-O-rutinoside).
Fig. 1
Some components such as 1,3-di-O-, 3,4-di-O-, 3,4,5-tri-O-caffeoyl-, 3-O-, 5-O-galloyl quinic acids, 1-O-caffeoylglucose, quercetin-3-O-gentiobioside, catechins (C, EC, EGC, EGCG) and procyanidins (B1, B2) were identified in F. ulmaria for the first time. The chemical composition research was done also for other plants of this genus such as F. denudata, F. palmata, F. vulgaris and the first time for F. camtschatica and F. stepposa.
|
Part of plant |
Flavonoids |
Ellagitannins |
Procyanidins |
Catechins |
|
Flowers |
19.11 – 74.05 |
40.01 – 207.31 |
- |
- |
|
Leaves |
18.35 – 43.15 |
9.15 – 52.13 |
20.31 – 37.05 |
18.63 – 103.14 |
Obtained data let suggest that ellagitannins tellimagrandin I2, rugosins E1, E2, and flavonoids spiraeoside and kaempferol-4′-O-glucoside can be considered as chemotaxonomic markers in Filipendula genus, apart from the previously proposed rugosin D.
The authors acknowledge for the financial support provided by the Russian Foundation of Basic Research under Project 12 – 03 – 31547.