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Synlett 2014; 25(09): 1279-1282
DOI: 10.1055/s-0033-1341159
DOI: 10.1055/s-0033-1341159
letter
Study of Oxidative Cyclization Using PhI(OAc)2 in the Formation of Benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles and Related Heterocycles – Scope and Limitations
Further Information
Publication History
Received: 14 March 2014
Accepted: 19 March 2014
Publication Date:
28 April 2014 (online)
Abstract
A one-pot, two-step reaction for the synthesis of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles and related heterocycles under mild conditions was herein developed. The key step of this transformation is an oxidative cyclization employing PhI(OAc)2 as reagent. Scope and limitations (group functionality tolerance and sterics) were studied showing the robustness of the present methodology which can be used as potential access to new fused heterocycle libraries.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information
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