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Synthesis 2014; 46(11): 1463-1468
DOI: 10.1055/s-0033-1341101
DOI: 10.1055/s-0033-1341101
paper
Facile Direct Synthesis of Acetylenedicarboxamides
Weitere Informationen
Publikationsverlauf
Received: 13. Januar 2014
Accepted after revision: 11. Februar 2014
Publikationsdatum:
17. März 2014 (online)
![](https://www.thieme-connect.de/media/synthesis/201411/lookinside/thumbnails/10.1055-s-0033-1341101-1.jpg)
Abstract
A convenient, rapid and widely applicable one-pot procedure has been developed for the synthesis of acetylenedicarboxamides from various primary and secondary amines, including amino acid derivatives, protected carbohydrates, and fluorescent labels. By using DMTMM for amide coupling, acetylenedicarboxylic acid was directly converted into acetylenedicarboxamides in highly competitive overall yields (52–80%).
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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