Synthesis 2014; 46(09): 1191-1196
DOI: 10.1055/s-0033-1340873
paper
© Georg Thieme Verlag Stuttgart · New York

Synthesis of 2,3-Unsaturated Glycosides and Disaccharides via Ruthenium(III)­ Chloride Catalyzed Ferrier Glycosylation

Batthula Srinivas
D-207, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, India   Fax: +91(40)27160387   Email: skashyap@iict.res.in
,
Gundeboina Narasimha
D-207, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, India   Fax: +91(40)27160387   Email: skashyap@iict.res.in
,
Palakodety Radha Krishna*
D-207, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, India   Fax: +91(40)27160387   Email: skashyap@iict.res.in
,
Sudhir Kashyap*
D-207, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, India   Fax: +91(40)27160387   Email: skashyap@iict.res.in
› Author Affiliations
Further Information

Publication History

Received: 10 December 2013

Accepted after revision: 06 February 2014

Publication Date:
05 March 2014 (online)


Abstract

A facile and stereoselective method for Ferrier glycosylation was developed using ruthenium(III) chloride. Using this protocol, the glycal donor reacted smoothly with several acceptors comprising different functionalities to afford corresponding 2,3-unsaturated glycosides in good to excellent yields.

Supporting Information

 
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