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Synlett 2014; 25(5): 741-745
DOI: 10.1055/s-0033-1340677
DOI: 10.1055/s-0033-1340677
letter
A Robust Route towards Functionalized Pyrrolizidines as Precursors for Daphniphyllum Alkaloids
Further Information
Publication History
Received: 05 November 2013
Accepted after revision: 03 January 2014
Publication Date:
13 February 2014 (online)
Abstract
A diastereoselective Fráter–Seebach-type alkylation provides access to a highly functionalized pyrrolizidine, which could serve as a key building block for the total synthesis of Daphniphyllum alkaloids, such as oldhamine A.
Key words
Daphniphyllum alkaloids - pyrrolizidines - heterocycles - asymmetric synthesis - oldhamine ASupporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information
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