A Mild, Room-Temperature Protection of Ketones and Aldehydes as 1,3-Dioxolanes under Basic Conditions

The authors became aware of some errors in the experimental section (note/reference 19). The correct general procedure should read:

Protection of 2 as 1,3-Dioxolane 3 (Table 1); General Procedure: A solution of ketone or aldehyde 2 (1 mmol), 1a (mp 109–110 °C, Sigma-Aldrich, 121 mg, 0.7 mmol), triethylamine (101 mg, 1 mmol), and ethylene glycol (124 mg, 2 mmol) in CH₂Cl₂ (4 mL) was stirred at r.t. for 10 min. The solution was washed with water and brine, and dried over anhydrous MgSO₄. Concentration under vacuum afforded 3. Flash chromatography (basic alumina; EtOAc–hexane, 1:9) gave pure 3 in 80–90% yield (Table 1). The analytical data of 1,3-dioxolanes 3 were in good agreement with those of authentic compounds.

The authors apologize.

Synlett 2012, 23, 2773.