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Synthesis 2013; 45(12): 1654-1658
DOI: 10.1055/s-0033-1338434
DOI: 10.1055/s-0033-1338434
special topic
Highly Enantioselective Michael Addition of α-Substituted Nitrophosphonates to a Vinyl Sulfone
Further Information
Publication History
Received: 08 March 2013
Accepted after revision: 02 April 2013
Publication Date:
17 April 2013 (online)
![](https://www.thieme-connect.de/media/synthesis/201312/lookinside/thumbnails/10.1055-s-0033-1338434-1.jpg)
Abstract
Organocatalytic asymmetric Michael reaction of α-substituted nitrophosphonates to phenyl vinyl sulfone catalyzed by cinchona alkaloid-derived tertiary amine-thioureas afforded α,α-disubstituted nitrophosphonates in very good yields and excellent enantiomeric excesses.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
-
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