Hypoglycemic and hypolipidemic activities of Myrcia bella cambess. in streptozotocin – diabetic mice

PMP Vareda; LL Saldanha; AL Dokkedal; JR Bosqueiro

doi:10.1055/s-0032-1320675

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Planta Med 2012; 78 - PH16
DOI: 10.1055/s-0032-1320675

Hypoglycemic and hypolipidemic activities of Myrcia bella cambess. in streptozotocin – diabetic mice

PMP Vareda ¹, LL Saldanha ¹, AL Dokkedal ², JR Bosqueiro ²

¹Institute of Biosciences, Botucatu
²Faculty of Science, UNESP, State University of São Paulo, Bauru, SP, Brazil

Congress Abstract

The aim of this study was to access the effects of M. bella on streptozotocin- diabetic mice. Male albino Swiss mice (90 days, 40g) were divided into 4 groups treated by gavage for 21 consecutive days: CTL SAL (control mice treated with saline), CTL EXT (control mice treated with M. bella extract, 600mg/Kg.day), STZ SAL (diabetic mice treated with saline) and STZ EXT (diabetic mice treated with M. bella extract, 600mg/Kg.day). STZ EXT had decreased glucose and lipid levels and also food and water intake compared with STZ SAL (P<0.05). The crude extract seems to be a valuable source of natural products that can act as a hypoglycemic and hypolipidemic agent.

* vs. STZ SAL, # vs. STZ EXT, & vs. CTL SAL