Synlett 2013; 24(1): 11-19
DOI: 10.1055/s-0032-1317481
account
© Georg Thieme Verlag Stuttgart · New York

Organocatalytic Asymmetric Synthesis and Use of Organoselenium Compounds

Francesca Marini*
Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, Via del Liceo, 06123 Perugia, Italy   Fax: +39(075)5855116   eMail: marini@unipg.it
,
Silvia Sternativo
Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, Via del Liceo, 06123 Perugia, Italy   Fax: +39(075)5855116   eMail: marini@unipg.it
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received: 25. Juli 2012

Accepted after revision: 24. September 2012

Publikationsdatum:
14. November 2012 (online)


Dedicated to our mentor Professor Marcello Tiecco

Abstract

In the last ten years organocatalysis has emerged as an efficient and sustainable strategy for the asymmetric synthesis of chiral molecules. Optically active intermediates for novel interesting transformations are generated under mild and operationally simple conditions when selenium-containing compounds are used as reaction partners. The peculiar reactivity of organoselenium compounds has been exploited in practical one-pot sequences for the asymmetric construction of densely functionalized compounds starting from simple precursors.

1 Introduction

2 Organocatalytic Asymmetric Synthesis of α-Seleno Carbonyl Compounds and Applications

3 Organocatalytic Additions to Vinyl Selenones for the Enantioselective Construction of Quaternary Stereocenters

4 Concluding Remarks