NbCl₅-Promoted Synthesis of 4-Aryl-3,4-dihydrocoumarins by Multicomponent Reaction

Abstract

Substituted 4-aryl-3,4-dihydrocoumarins are synthesized from multicomponent reactions between phenols, dimethyl malonate, and aryl aldehydes catalyzed by niobium pentachloride. This new method is simple, cost-effective, and high-yielding, and can be conducted in acceptable reaction times.

Key words

niobium pentachloride - multicomponent reaction - coumarin derivatives - Lewis acid - phenols

• References

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