Catalyst-Free Amidation of Trimethylsilyl Ketene Imines with Isocyanates

Abstract

A catalyst-free method for the amidation of N-trimethylsilyl ketene imines using isocyanates is reported. A working hypothesis on the reaction pathway includes silatropism from the ketene nitrogen to the isocyanate oxygen as the driving force of the process.

Key words

nitriles - ketene imines - isocyanates - silatropism - amidation

• References

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