The Thrombostat 4000 was used to investigate primary hemostasis in women during ditTerent stages of their life cycle. Nonpregnant females were studied during their proliferative and luteal phases; pregnant women were investigated during their 2–35th weeks of gestation and some women between the ages of 70–84. Data were compared to those obtained from male volunteers injected with 40 mg estrogen. No significant ditTerences between proliferative and luteal phases were found, but BT2 was prolonged in the elderly women. In the pregnant women extremely short BT2 values were measured. Shortening of BT2 was also seen in the males injected with estrogen.
Keywords
Thrombostat - estrogen - pregnancy - primary hemostasis - hypercoagulability