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DOI: 10.1055/s-0031-1298539
Sesquiterpenoids from the Rhizomes of Homalomena occulta
Publication History
received 25 February 2012
revised 15 March 2012
accepted 16 April 2012
Publication Date:
09 May 2012 (online)
![](https://www.thieme-connect.de/media/plantamedica/201210/lookinside/thumbnails/10.1055-s-0031-1298539-1.jpg)
Abstract
Phytochemical investigation on the rhizomes of Homalomena occulta resulted in the isolation of five new sesquiterpenoids, namely cadinane-4β,5α,10α-triol (1), 5(11)-epoxycadinane-4β,5β,10β,11-tetraol (2), bullatantiol-1β-methyl malate (3), 1β,4β,7α-trihydroxyeudesmane-1β-methyl malate (6), and 1β,4α,7-trihydroxyeudes-mane (7), together with five known sesquiterpenoids, bullatantriol (4), acetylbullatantriol (5), 1β,4β,7α-trihydroxyeudesmane (8), 1β,4β,7β-trihydroxyeude-smane (9), and pterodontriol (10). Their structures were elucidated on the basis of spectroscopic evidences, including various 1D and 2D NMR and HR-ESI-MS. The structure of 1 was further confirmed by single-crystal X-ray diffraction analysis.
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