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Synlett 2012(5): 765-767
DOI: 10.1055/s-0031-1290598
DOI: 10.1055/s-0031-1290598
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New York
Investigation of Additive Effects in Enantioselective Copper-Catalysed C-H Insertion and Aromatic Addition Reactions of α-Diazocarbonyl Compounds
Weitere Informationen
Received
4 November 2011
Publikationsdatum:
28. Februar 2012 (online)
Publikationsverlauf
Publikationsdatum:
28. Februar 2012 (online)
![](https://www.thieme-connect.de/media/synlett/201205/lookinside/thumbnails/10.1055-s-0031-1290598-1.jpg)
Abstract
Significant enhancements in enantioselectivities and reaction efficiencies in asymmetric copper-catalysed C-H insertion and aromatic addition reactions of α-diazocarbonyl compounds in the presence of various group I salts are reported. For the first time in carbenoid chemistry, evidence for the critical role of the metal cation is described.
Key words
diazocarbonyl - copper catalysis - C-H insertion - Buchner reaction - bis(oxazoline) ligands
- Supporting Information for this article is available online:
- Supporting Information
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References and Notes
Presence of NaCl confirmed by PXRD analysis (see Supporting Information for details).