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Synlett 2012(2): 255-258
DOI: 10.1055/s-0031-1290073
DOI: 10.1055/s-0031-1290073
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New York
One-Pot Synthesis of Fused Pyridazino[4,5-b][1,4]oxazepine-diones via Smiles Rearrangement
Weitere Informationen
Received
6 September 2011
Publikationsdatum:
03. Januar 2012 (online)
Publikationsverlauf
Publikationsdatum:
03. Januar 2012 (online)
![](https://www.thieme-connect.de/media/synlett/201202/lookinside/thumbnails/10.1055-s-0031-1290073-1.jpg)
Abstract
Fused pyridazino[4,5-b][1,4]oxazepine-diones were easily obtained in moderate to excellent yields via Smiles rearrangement. The synthetic approach is supported by a one-pot coupling-Smiles rearrangement-cyclization process. This process has potential applications in the synthesis of biologically and medicinally relevant compounds.
Key words
pyridazino[4,5-b][1,4]oxazepine-dione - one-pot - synthesis - Smiles rearrangement - tandem reaction
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