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Synlett 2011(20): 2991-2994
DOI: 10.1055/s-0031-1289883
DOI: 10.1055/s-0031-1289883
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New York
Iron-Mediated Cyanation of Methoxybenzene, Indole, and 2-Arylpyridine C-H Bonds
Further Information
Publication History
Received
4 September 2011
Publication Date:
11 November 2011 (online)


Abstract
An iron-mediated direct cyanation of indole and 2-arylpyridine C-H bonds is described. Notably, trimethoxybenzene reacted smoothly under the procedure, forming a C-CN bond via C-H bond cleavage without chelation assistance.
Key words
iron - indole - 2-arylpyridine - C-H activation - cyanation
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