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DOI: 10.1055/s-0031-1287867
Organ Failure: Central Nervous System
Publication History
Publication Date:
11 October 2011 (online)
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ABSTRACT
Central nervous system (CNS) failure represents a spectrum of disease ranging from mild neurological impairment that may have motor, sensory, visual, speech, cognitive manifestations, or a combination thereof, to comatose states and brain death. This article summarizes the common causes of CNS failure and analyzes the role of clinical, radiological, laboratory, and other ancillary testing in establishing the underlying diagnosis and assessing severity of CNS failure in each condition; we also comment on various treatment options for each of the causes of CNS failure.
KEYWORDS
Central nervous system failure - subarachnoid hemorrhage - intracerebral hemorrhage - ischemic stroke - traumatic brain injury - anoxic brain injury - status epilepticus - encephalopathy
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Marek MirskiM.D. Ph.D.
Neurosciences: Department of Anesthesiology/Critical Care Medicine, Neurology, Neurosurgery; Johns Hopkins University School of Medicine
600 N. Wolfe St., Meyer 8-140, Baltimore, MD 21287
Email: mmirski@jhmi.edu