Subscribe to RSS
DOI: 10.1055/s-0031-1278364
© Georg Thieme Verlag KG Stuttgart · New York
Adverse effect of low-dose amiodarone mimicking pulmonary malignancy
Publication History
Publication Date:
28 April 2011 (online)
![](https://www.thieme-connect.de/media/ija/201001/lookinside/thumbnails/10.1055-s-0031-1278364-1.jpg)
Abstract
A 74-year-old woman presented with a one-week history of persistent cough. A chest x-ray and computed tomography images revealed features mimicking lung cancer, which included a large solitary consolidation and hilar lymphadenopathy. She had received low-dose amiodarone (200 mg/day) for treatment of atrial fibrillation for more than 2.5 years. The tumour-like abnormalities did not disappear until the discontinuation of amiodarone therapy. The finding of low-dose amiodarone causing tumour-like abnormalities on a chest x-ray is unique. Once amiodarone-induced tumour-like changes are diagnosed, therapeutic options are limited. In most cases, the tumour-like changes are reversible, if diagnosed early. An unusual case involving amiodarone induced pulmonary abnormalities is reported, followed by a review of the relevant literature.