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Klin Padiatr 2011; 223(7): 434-435
DOI: 10.1055/s-0031-1277216
DOI: 10.1055/s-0031-1277216
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© Georg Thieme Verlag KG Stuttgart · New York
Severe Rhabdomyolysis Caused by Valproic Acid in a Neonate with Seizures and Chromosomal Abnormalities
Schwere Rhabdomyolyse nach Valproat-Therapie bei einem Neugeborenen mit Krampfanfällen und ChromosomenanomalieWeitere Informationen
Publikationsverlauf
Publikationsdatum:
25. Mai 2011 (online)
![](https://www.thieme-connect.de/media/klinpaed/201107/lookinside/thumbnails/10.1055-s-0031-1277216-1.jpg)
Key words
valproic acid - rhabdomyolysis - neonate - chromosomal abnormalities
Schlüsselwörter
Valproinsäure - Rhabdomyolyse - Neugeborenes - chromosomale Veränderungen
References
- 1 Kottlors M, Jaksch M, Ketelsen UP. et al . Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency. Neuromusc Disord. 2001; 11 757-759
- 2 Lheureux PE, Hantson P. Carnitine in the treatment of valproic acid-induced toxicity. Clin Toxicol. 2009; 47 101-111
- 3 Meyer S, Kuhlmann MK, Peters FT. et al . Severe valproic acid intoxication is associated with atrial tachycardia: secondary detoxicaton by hemoperfusion. Klin Padiatr. 2005; 217 82-85
- 4 Naranjo CA, Busto U, Sellers EM. et al . A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981; 30 239-245
- 5 Prandstetter C, Tamesberger M, Wagner. et al . Medical prescriptions to premature and newborn infants in an Austrian neonatal intensive care unit. Klin Padiatr. 2009; 221 312-317
- 6 Roth B. Off-label and unlicenced use of drugs in neonatal intensive care. Klin Padiatr. 2009; 22 275-277
Correspondence
PD Dr. Sascha MeyerMD
Department of Pediatric and
Neonatal Intensive Care
University Hospital of Saarland
Building 9
Kirrbergerstraße
66421 Homburg
Germany
Telefon: +49/6841/162 83 74
Fax: +49/6841/162 83 63
eMail: sascha.meyer@uniklinikum-saarland.de