Das PECom des Uterus – ein seltener mesenchymaler Tumor: Fallbericht und Literaturübersicht

Zusammenfassung

PECome des Uterus sind seltene mesenchymale Tumoren, ausgehend von perivaskulären, glattmuskulär differenzierten Zellen mit epitheloider Morphologie und immunhistochemischer Koexpression von glattmuskulären und melanozytären Markern. Mit einer Gesamtüberlebensrate von 92 % ist die Prognose gut und die Majorität der PECome ist als „low grade“-Läsion einzuordnen. Dennoch wird ein engmaschiges Follow-up empfohlen. Die Stadieneinteilung sollte nach Art der Leiomyosarkome erfolgen. Der vorliegende Fall wurde bei einer 65-jährigen Frau beobachtet mit einer maximalen Tumorgröße von 6 cm mit Infiltration adnexaler Mesostrukturen.

Abstract

Perivascular epithelioid cell tumor (PEComa) of the uterus is a rare mesenchymal lesion characterized by a proliferation of perivascular epitheloid cells with eosinophilic cytoplasm and immunohistochemical coexpression of both smooth muscle and melanocytic markers. The majority (∼ 92 %) of PEComas exhibit a benign behavior and are considered low-grade lesions. Nevertheless, a close follow-up of patients is necessary, and tumors should be staged like leiomyosarcomas. The presented case of a 65-year-old woman revealed a PEComa with diameter of 6 cm and adnexal involvement.

Schlüsselwörter

Tumor - Uterus - mesenchymaler Tumor - PEComa

Key words

perivascular epitheloid cell tumor - PEComa - uterus - mesenchymal tumor

Literatur

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