Kasuistik: Rapid Sequence Induction – Reversion einer tiefen neuromuskulären Blockade durch Sugammadex

Zusammenfassung

Sugammadex reversiert die Wirkung von Rocuronium durch Enkapsulierung ohne muskarinerge Nebenwirkungen. Bisherige publizierte Studien zeigen eine effektive dosisabhängige Reversierung der neuromuskulären Blockade nach Verwendung von Rocuronium oder Vecuronium. Wir berichten in unserem Fallbericht von einem Patienten, der am Ende der OP nach RSI mit Rocuronium eine tiefe neuromuskuläre Blockade zeigte, die innerhalb weniger Minuten nebenwirkungsfrei reversiert werden konnte.

Abstract

Sugammadex can reverse rocuronium-induced muscular relaxation by encapsulation of steroidal muscle relaxants without muscarinergic side effects. Clinical studies show effective dose-dependent reversal of neuromuscular blockades after rocuronium and vecuronium. We report on a patient with deep neuromuscular block at the end of surgery following rapid sequence induction of anesthesia with high-dose rocuronium, who could rapidly be reversed without side effects after adequate i.v. sugammadex application.

Schlüsselwörter

neuromuskuläre Blockade - Rocuronium - Sugammadex - Muskelrelaxans - postoperative Restcurarisierung - Rapid Sequence Induction

Key words:

muscle relaxant - neuromuscular block - sugammadex - rocuronium - rapid sequence induction - postoperative residual neuromuscular block

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