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Exp Clin Endocrinol Diabetes 2011; 119(3): 163-166
DOI: 10.1055/s-0030-1262790
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Effects of Exercise on the Levels of Peptide YY and Ghrelin

J.-B. Li1 , A. Asakawa1 , Y. Li1 , K. Cheng1 , A. Inui1
  • 1Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan
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Publikationsverlauf

received 12.04.2010 first decision 31.05.2010

accepted 01.07.2010

Publikationsdatum:
05. August 2010 (online)

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Abstract

Ghrelin and peptide YY (PYY) are brain-gut peptides that have a variety of physiological functions and are involved in energy regulation. Thus far, abnormalities in the expression and secretion of ghrelin and PYY are known to occur in lifestyle-related diseases, including obesity, and the improvement of these abnormalities has become an important challenge. Exercise has recently been reported to influence ghrelin and PYY concentrations. Exercise increases the PYY secretion. The effects of exercise on ghrelin levels vary with the study subject, timing of exercise, and duration of exercise. Here, we review the findings of recent studies on the association of PYY and ghrelin with obesity, particularly, on the influence of exercise on PYY and ghrelin levels.

Key words

ghrelin - PYY - exercise - obesity - lifestyle-related disease

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Correspondence

A. AsakawaMD, PhD 

Department of Psychosomatic

Internal Medicine

Kagoshima University Graduate

School of Medical and Dental

Sciences

Sakuragaoka 8-35-1

890-8520 Kagoshima

Japan

Telefon: +81/99/275 5751

Fax: +81/99/275 5749

eMail: asakawa@m2.kufm.kagoshima-u.ac.jp