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Synfacts 2011(7): 0776-0776
DOI: 10.1055/s-0030-1260501
DOI: 10.1055/s-0030-1260501
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Pd-Catalyzed Decarboxylative Cross-Coupling to Yield Aryl Ketones
M. Li, C. Wang, H. Ge*
Indiana University Purdue University Indianapolis, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
17. Juni 2011 (online)
Significance
A novel palladium-catalyzed decarboxylative cross-coupling of potassium aryltrifluoroborates with α-oxocarboxylic acids to afford aryl ketones has been disclosed. A combination of catalytic Pd(OAc)2 with stoichiometric K2S2O8 was found to be the most efficient system for the reaction.